ZK 200775
- Product Name
- ZK 200775
- CAS No.
- 161605-73-8
- Chemical Name
- ZK 200775
- Synonyms
- MPQX;ZK 200775;Fanapanel;Fanapanel(ZK200775);MPQX;ZK200775;ZK-200775;7-Morpholino-2,3-dioxo-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-1-ylmethylphosphonic acid;((7-morpholino-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)methyl)phosphonic acid;[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonicacid;[[3,4-DIHYDRO-7-(4-MORPHOLINYL)-2,3-DIOXO-6-(TRIFLUOROMETHYL)-1(2H)-QUINOXALINYL]METHYL]PHOSPHONIC ACID;P-[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid
- CBNumber
- CB9848467
- Molecular Formula
- C14H15F3N3O6P
- Formula Weight
- 409.25
- MOL File
- 161605-73-8.mol
ZK 200775 Property
- Density
- 1.615±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO: ≥20mg/mL
- pka
- 2.09±0.10(Predicted)
- form
- powder
- color
- off-white to light brown
Safety
- WGK Germany
- 3
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 2345
- Product name
- ZK200775
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $223
- Updated
- 2021/12/16
- Product number
- 2345
- Product name
- ZK200775
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $934
- Updated
- 2021/12/16
- Product number
- 257170
- Product name
- ZK 200775
- Packaging
- 10mg
- Price
- $502
- Updated
- 2021/12/16
- Product number
- Z485903
- Product name
- ZK200775(Fanapanel)
- Packaging
- 1mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- Z485903
- Product name
- ZK200775(Fanapanel)
- Packaging
- 2.5mg
- Price
- $165
- Updated
- 2021/12/16
ZK 200775 Chemical Properties,Usage,Production
Uses
ZK 200775 is a competitive AMPA/kainate antagonist. Neuronal protection against cerebral ischemia.
Biological Activity
Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [ 3 H]-AMPA (K i = 120 nM) and [ 3 H]-CNQX (K i = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC 50 values range from 2.5 to 11 μ M). Inhibits currents induced by AMPA, kainate and NMDA with IC 50 values of 21 nM, 27 nM, and > 1 μ M respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo .
storage
Desiccate at +4°C
ZK 200775 Preparation Products And Raw materials
Raw materials
Preparation Products
ZK 200775 Suppliers
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