ChemicalBook > CAS DataBase List > ZK 200775

ZK 200775

Product Name
ZK 200775
CAS No.
161605-73-8
Chemical Name
ZK 200775
Synonyms
MPQX;ZK 200775;Fanapanel;Fanapanel(ZK200775);MPQX;ZK200775;ZK-200775;7-Morpholino-2,3-dioxo-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-1-ylmethylphosphonic acid;((7-morpholino-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)methyl)phosphonic acid;[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonicacid;[[3,4-DIHYDRO-7-(4-MORPHOLINYL)-2,3-DIOXO-6-(TRIFLUOROMETHYL)-1(2H)-QUINOXALINYL]METHYL]PHOSPHONIC ACID;P-[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid
CBNumber
CB9848467
Molecular Formula
C14H15F3N3O6P
Formula Weight
409.25
MOL File
161605-73-8.mol
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ZK 200775 Property

Density 
1.615±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO: ≥20mg/mL
pka
2.09±0.10(Predicted)
form 
powder
color 
off-white to light brown
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Safety

WGK Germany 
3
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
2345
Product name
ZK200775
Purity
≥99%(HPLC)
Packaging
10
Price
$223
Updated
2021/12/16
Tocris
Product number
2345
Product name
ZK200775
Purity
≥99%(HPLC)
Packaging
50
Price
$934
Updated
2021/12/16
Usbiological
Product number
257170
Product name
ZK 200775
Packaging
10mg
Price
$502
Updated
2021/12/16
TRC
Product number
Z485903
Product name
ZK200775(Fanapanel)
Packaging
1mg
Price
$85
Updated
2021/12/16
TRC
Product number
Z485903
Product name
ZK200775(Fanapanel)
Packaging
2.5mg
Price
$165
Updated
2021/12/16
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ZK 200775 Chemical Properties,Usage,Production

Uses

ZK 200775 is a competitive AMPA/kainate antagonist. Neuronal protection against cerebral ischemia.

Biological Activity

Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [ 3 H]-AMPA (K i = 120 nM) and [ 3 H]-CNQX (K i = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC 50 values range from 2.5 to 11 μ M). Inhibits currents induced by AMPA, kainate and NMDA with IC 50 values of 21 nM, 27 nM, and > 1 μ M respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo .

storage

Desiccate at +4°C

ZK 200775 Preparation Products And Raw materials

Raw materials

Preparation Products

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ZK 200775 Suppliers

China 39 Germany 1 United Kingdom 1 United States 12 Global 53
Shanghai Boyle Chemical Co., Ltd.
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RD International Technology Co., Limited
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161605-73-8, ZK 200775Related Search:

2,3-Quinoxalinedione,6-amino-1,4-dihydro-(9CI) 1,2,3,4-Tetrahydro-quinoxalin-6-ylamine ZK 200775 2-Amino-5-acetamidobenzotrifluoride

  • [[3,4-DIHYDRO-7-(4-MORPHOLINYL)-2,3-DIOXO-6-(TRIFLUOROMETHYL)-1(2H)-QUINOXALINYL]METHYL]PHOSPHONIC ACID
  • ZK 200775
  • [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonicacid
  • Fanapanel
  • MPQX
  • 7-Morpholino-2,3-dioxo-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-1-ylmethylphosphonic acid
  • [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]-phosphonic acid hydrate
  • P-[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid
  • Phosphonic acid, P-[[3,4-dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]-
  • MPQX;ZK200775;ZK-200775
  • Fanapanel(ZK200775)
  • ((7-morpholino-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)methyl)phosphonic acid
  • 161605-73-8
  • C14H15F3N3O6P
  • C14H15N3O6F3P