2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE

Product Name: 2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE
CAS No.: 70006-24-5
Chemical Name: 2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE
Synonyms: ABT 724;ABT 724 TRIHYDROCHLORIDE;2-[[4-(2-Pyridinyl)-1-piperazinyl]Methyl]-1H-benziMidazole;1H-Benzimidazole, 2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-;2-((4-(Pyridin-2-yl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole;2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE;ABT 724,Inhibitor,Dopamine Receptor,penile,erection,D4-receptor,Dopamine,ABT-724,inhibit,ABT724,potentiation,side-effect
CBNumber: CB9850686
Molecular Formula: C17H19N5
Formula Weight: 293.37
MOL File: 70006-24-5.mol

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2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE Property

storage temp.: Inert atmosphere,2-8°C
form: solid
color: White

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Tocris

Product number: 2214
Product name: ABT-724 trihydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $144
Updated: 2021/12/16

Tocris

Product number: 2214
Product name: ABT-724 trihydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $603
Updated: 2021/12/16

TRC

Product number: A112605
Product name: ABT724
Packaging: 50mg
Price: $100
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0000085
Product name: ABT-724
Purity: 95.00%
Packaging: 10MG
Price: $697.34
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0000085
Product name: ABT-724
Purity: 95.00%
Packaging: 50MG
Price: $1170.31
Updated: 2021/12/16

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2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

ABT 724 trihydrochloride is a potent dopamine D4 receptor agonist. ABT 724 is used in pharmacology systems for treating ocular disorders.

Definition

ChEBI: 2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1H-benzimidazole is a member of pyridines and a member of piperazines.

Biological Activity

Potent dopamine D 4 receptor partial agonist (EC 50 = 12.4 nM; 61% efficacy vs. dopamine). Has no agonist activity at D 2 receptors (EC 50 > 10 μ M). Selective in rats in vivo : produces penile erection following i.c.v. administration; increases intracavernosal pressure and potentiates the proerectile effects of sildenafil following s.c. administration. Displays minimal side effects.

2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE Suppliers

China 39 Germany 1 United Kingdom 1 United States 6 Global 47

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70006-24-5, 2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDERelated Search:

2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE

ABT 724 TRIHYDROCHLORIDE

2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE

2-[[4-(2-Pyridinyl)-1-piperazinyl]Methyl]-1H-benziMidazole

ABT 724

1H-Benzimidazole, 2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-

ABT 724,Inhibitor,Dopamine Receptor,penile,erection,D4-receptor,Dopamine,ABT-724,inhibit,ABT724,potentiation,side-effect

2-((4-(Pyridin-2-yl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

70006-24-5

C17H22Cl3N5

C17H19N53HCl