2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE
- Product Name
- 2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE
- CAS No.
- 70006-24-5
- Chemical Name
- 2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE
- Synonyms
- ABT 724;ABT-724, 10 mM in DMSO;ABT 724 TRIHYDROCHLORIDE;2-[[4-(2-Pyridinyl)-1-piperazinyl]Methyl]-1H-benziMidazole;1H-Benzimidazole, 2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-;2-((4-(Pyridin-2-yl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole;2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE;ABT 724,Inhibitor,Dopamine Receptor,penile,erection,D4-receptor,Dopamine,ABT-724,inhibit,ABT724,potentiation,side-effect
- CBNumber
- CB9850686
- Molecular Formula
- C17H19N5
- Formula Weight
- 293.37
- MOL File
- 70006-24-5.mol
2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE Property
- storage temp.
- Inert atmosphere,2-8°C
- form
- solid
- color
- White
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 2214
- Product name
- ABT-724 trihydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $144
- Updated
- 2021/12/16
- Product number
- 2214
- Product name
- ABT-724 trihydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $603
- Updated
- 2021/12/16
- Product number
- A112605
- Product name
- ABT724
- Packaging
- 50mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- BRS0000085
- Product name
- ABT-724
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $697.34
- Updated
- 2021/12/16
- Product number
- BRS0000085
- Product name
- ABT-724
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $1170.31
- Updated
- 2021/12/16
2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE Chemical Properties,Usage,Production
Uses
ABT 724 trihydrochloride is a potent dopamine D4 receptor agonist. ABT 724 is used in pharmacology systems for treating ocular disorders.
Definition
ChEBI: 2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1H-benzimidazole is a member of pyridines and a member of piperazines.
Biological Activity
Potent dopamine D 4 receptor partial agonist (EC 50 = 12.4 nM; 61% efficacy vs. dopamine). Has no agonist activity at D 2 receptors (EC 50 > 10 μ M). Selective in rats in vivo : produces penile erection following i.c.v. administration; increases intracavernosal pressure and potentiates the proerectile effects of sildenafil following s.c. administration. Displays minimal side effects.
2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71