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quinisocaine

Product Name
quinisocaine
CAS No.
86-80-6
Chemical Name
quinisocaine
Synonyms
Pruralgin;Pruralgan;quinisocaine;Dimethisoquin;3-Butyl-1-[2-(dimethylamino)ethoxy]isoquinoline;{2-[(3-butylisoquinolin-1-yl)oxy]ethyl}dimethylamine;2-(3-butylisoquinolin-1-yl)oxy-N,N-dimethylethanamine;2-[(3-Butyl-1-isoquinolyl)oxy]-N,N-dimethylethanamine;Ethanamine, 2-[(3-butyl-1-isoquinolinyl)oxy]-N,N-dimethyl-
CBNumber
CB9881536
Molecular Formula
C17H24N2O
Formula Weight
272.39
MOL File
86-80-6.mol
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quinisocaine Property

Melting point:
146°C
Boiling point:
bp3 155-157°
Density 
0.9848 (rough estimate)
refractive index 
nD20 1.5486
pka
pKa 6.30 (Uncertain)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015494
Product name
QUINISOCAINE
Purity
95.00%
Packaging
5MG
Price
$498.1
Updated
2021/12/16
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quinisocaine Chemical Properties,Usage,Production

Originator

Quotane,SKF,US,1951

Definition

ChEBI: 2-[(3-butyl-1-isoquinolinyl)oxy]-N,N-dimethylethanamine is a member of isoquinolines.

Manufacturing Process

A mixture of 10.0 grams of β-dimethylaminoethanol and 1.9 grams of sodium in 90 cc of dry xylene was heated at 95°C for 5 hours. To the resulting solution was added at 30°C, 18 grams of 3-butyl-1-chloroisoquinoline. The solution, which turned very dark, was heated at 100°-125°C for 3.5 hours. The mixture was extracted with two 100 cc portions of 2N hydrochloric acid solution. The acid solution was made strongly alkaline with 40% potassium hydroxide solution and the oil which separated was taken into ether. The ether solution was washed with two 100 cc portions of water saturated with sodium chloride, and then dried over anhydrous sodium sulfate for 3 hours. The sodium sulfate was removed by filtration and the ether by distillation. Distillation of the residual oil gave a colorless liquid, BP 155°-157°C/3mm.

Therapeutic Function

Local anesthetic

quinisocaine Preparation Products And Raw materials

Raw materials

Preparation Products

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quinisocaine Suppliers

Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Shaanxi Didu New Material Co., Ltd
Tel
029-81145920 15353716720
Email
1046@dideu.com
Country
China
ProdList
9983
Advantage
58
Shaanxi Didu New Materials Co. Ltd
Tel
+86-89586680 +86-13289823923
Email
1026@dideu.com
Country
China
ProdList
8670
Advantage
58

86-80-6, quinisocaineRelated Search:


  • quinisocaine
  • Dimethisoquin
  • 2-[(3-Butyl-1-isoquinolyl)oxy]-N,N-dimethylethanamine
  • 3-Butyl-1-[2-(dimethylamino)ethoxy]isoquinoline
  • Pruralgan
  • Pruralgin
  • {2-[(3-butylisoquinolin-1-yl)oxy]ethyl}dimethylamine
  • 2-(3-butylisoquinolin-1-yl)oxy-N,N-dimethylethanamine
  • Ethanamine, 2-[(3-butyl-1-isoquinolinyl)oxy]-N,N-dimethyl-
  • 86-80-6