Hydroxy-PEG16-t-butyl ester

Product Name: Hydroxy-PEG16-t-butyl ester
CAS No.: 2592433-80-0
Chemical Name: Hydroxy-PEG16-t-butyl ester
Synonyms: Hydroxy-PEG16-t-butyl ester ISO 9001：2015 REACH;tert-Butyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48-hexadecaoxahenpentacontan-51-oate;4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49-Hexadecaoxahenpentacontanoic acid, 51-hydroxy-, 1,1-dimethylethyl ester;tert-butyl 42-(2-hydroxyethyl)-1-(l1-oxidaneyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42l3,45-pentadecaoxaoctatetracontan-48-oate
CBNumber: CB99023924
Molecular Formula: C39H78O19
Formula Weight: 851.03
MOL File: 2592433-80-0.mol

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Hydroxy-PEG16-t-butyl ester Property

Boiling point:: 774.9±55.0 °C(Predicted)
Density: 1.097±0.06 g/cm3(Predicted)
pka: 14.36±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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Hydroxy-PEG16-t-butyl ester Chemical Properties,Usage,Production

Uses

Hydroxy-PEG16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Hydroxy-PEG16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs; Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Hydroxy-PEG16-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxy-PEG16-t-butyl ester Suppliers

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Xi'an Confluore Biological Technology Co., Ltd.

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View Lastest Price from Hydroxy-PEG16-t-butyl ester manufacturers

LAURENT

Product: HO-PEG16-CH2CH2COOtBu 2592433-80-0
Price: US $2338.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-18

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: tert-butyl 42-(2-hydroxyethyl)-1-(l1-oxidaneyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42l3,45-pentadecaoxaoctatetracontan-48-oate 2592433-80-0
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

Xian confluore Biological Technology Co., Ltd.

Product: Hydroxy-PEG16-t-butyl ester 2592433-80-0
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-03-27

2592433-80-0, Hydroxy-PEG16-t-butyl esterRelated Search:

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Hydroxy-PEG16-t-butyl ester ISO 9001：2015 REACH

4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49-Hexadecaoxahenpentacontanoic acid, 51-hydroxy-, 1,1-dimethylethyl ester

tert-Butyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48-hexadecaoxahenpentacontan-51-oate

tert-butyl 42-(2-hydroxyethyl)-1-(l1-oxidaneyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42l3,45-pentadecaoxaoctatetracontan-48-oate

2592433-80-0