ChemicalBook > CAS DataBase List > cyamemazine

cyamemazine

Product Name
cyamemazine
CAS No.
3546-03-0
Chemical Name
cyamemazine
Synonyms
TH-2602;RP-7204;Tercian;7204 RP;CiaMatil;Cianatil;CyaMeMazin;F. I. 6229;7204 R. E.;cyamemazine
CBNumber
CB9914843
Molecular Formula
C19H21N3S
Formula Weight
323.46
MOL File
3546-03-0.mol
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cyamemazine Property

Melting point:
90-95°C
Boiling point:
bp0.2-0.5 205-220°
Density 
1.21±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO: ≥5mg/mL
pka
9.31±0.28(Predicted)
form 
powder
color 
light yellow to yellow-green
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Safety

Hazard Codes 
Xi,N
Risk Statements 
50
Safety Statements 
61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
Toxicity
LDLo oral in man: 107mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0321
Product name
Cyamemazine
Purity
≥98% (HPLC)
Packaging
10mg
Price
$144
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0321
Product name
Cyamemazine
Purity
≥98% (HPLC)
Packaging
50mg
Price
$572
Updated
2024/03/01
TRC
Product number
C951500
Product name
Cyamemazine
Packaging
25mg
Price
$190
Updated
2021/12/16
TRC
Product number
C951500
Product name
Cyamemazine
Packaging
50mg
Price
$360
Updated
2021/12/16
AK Scientific
Product number
1837BA
Product name
Cyamemazine
Packaging
25mg
Price
$488
Updated
2021/12/16
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cyamemazine Chemical Properties,Usage,Production

Chemical Properties

Greenish Yellow Solid

Originator

Terckian,Theraplix,France,1972

Uses

Cyamemazine is an anxiolytic antipsychotic, which reduces ethanol withdrawal symptoms.

Definition

ChEBI: Cyamemazine is a member of phenothiazines.

Manufacturing Process

The following is taken from US Patent 3,057,851. Milorganite was extracted with water to obtain an aqueous extract containing vitamin B12 active substances. This aqueous extract was purified by treatment with an ion exchange resin according to the following method. An aqueous extract of milorganite, 100 ml containing 300 μg of vitamin B12 active substances and 4.5 grams of total solids, was combined with 0.5 gram of sodium nitrite and 0.4 gram of potassium cyanide. The resulting solution was adjusted to pH 4.0 with hydrochloric acid and heated to boiling. The boiled solution was filtered through a Super-Cel filter surface, and the filter was then washed with water. The filtrate was obtained in a total volume of 130 ml including the washings.
Amerlite XE-97, an ion exchange resin of the carboxyl type (Rohm and Haas), was classified to an average wet particle size of 100 to 150 mesh. The classified resin was utilized in the hydrogen form, and was not buffered during the ion exchange fractionation. The classified resin, in the amount of 35 ml, was packed into a glass column having a diameter of 25 mm and a height of 250 mm. The cyanide-treated aqueous extract of milorganite was infused gravitationally into the ion exchange bed at a rate of 3 ml per minute.
The effluent was discarded and the resin bed was then washed with the following solutions in the specified sequence: (1) 120 ml of an aqueous 0.1 N hydrochloric acid solution; (2) 75 ml of an aqueous 85% acetone solution; and (3) 70 ml of an aqueous 0.1 N hydrochloric acid solution. After washing, the resin bed was eluted with an aqueous 60% dioxane solution containing 0.1 N of hydrochloric acid. In this elution, 8 ml of colored eluate was collected. This portion of the eluate was found to contain 295 μg of cyanocobalamin and 9 mg of total solids.

Therapeutic Function

Tranquilizer

cyamemazine Preparation Products And Raw materials

Raw materials

Preparation Products

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cyamemazine Suppliers

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View Lastest Price from cyamemazine manufacturers

Wuhan Monad Medicine Tech Co.,LTD
Product
Cyamemazine 3546-03-0
Price
US $50.00/KG
Min. Order
1Kg/Bag
Purity
99.99%
Supply Ability
20 tons/month
Release date
2021-04-19

3546-03-0, cyamemazine Related Search:


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  • RP-7204
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  • 2-Cyano-10-(3-diMethylaMino-2-Methylpropyl)phenothiazine
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