ChemicalBook > CAS DataBase List > 2-[(dimethylamino)methyl]cyclohexan-1-one

2-[(dimethylamino)methyl]cyclohexan-1-one

Product Name
2-[(dimethylamino)methyl]cyclohexan-1-one
CAS No.
15409-60-6
Chemical Name
2-[(dimethylamino)methyl]cyclohexan-1-one
Synonyms
Tramadol Impurity E (Y0000157);dimethylaminomethyl cyclohexanone;2-(Dimethylamino)methylcyclohexanone;2-(BisMethyl)aMinoMethylcyclohexanone;Cyclohexanone,2-[(diMethylaMino)Methyl]-;2-[(dimethylamino)methyl]cyclohexan-1-one;2-((DIMETHYLAMINO)METHYL)CYCLOHEXANONE(WXG01629);2-[(N,N-DIMETHYLAMINO)METHYL]-CYCLOHEXANONE HYDROCHLORIDE
CBNumber
CB9918083
Molecular Formula
C9H17NO
Formula Weight
155.24
MOL File
15409-60-6.mol
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2-[(dimethylamino)methyl]cyclohexan-1-one Property

Melting point:
148-150 °C
Boiling point:
222℃
Density 
0.944
refractive index 
1.4672
Flash point:
70℃
storage temp. 
2-8°C
pka
8.83±0.28(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S703451
Product name
2-(DIMETHYLAMINOMETHYL)-1-CYCLOHEXANONE
Purity
AldrichCPR
Packaging
50MG
Price
$29.8
Updated
2024/03/01
TRC
Product number
B585415
Product name
2-(Bismethyl)aminomethylcyclohexanone
Packaging
2.5g
Price
$165
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004463
Product name
TRAMADOL IMPURITY E
Purity
95.00%
Packaging
1G
Price
$780.15
Updated
2021/12/16
Ambeed
Product number
A827112
Product name
2-((Dimethylamino)methyl)cyclohexanone
Purity
95+%
Packaging
100mg
Price
$125
Updated
2021/12/16
Ambeed
Product number
A827112
Product name
2-((Dimethylamino)methyl)cyclohexanone
Purity
95+%
Packaging
250mg
Price
$178
Updated
2021/12/16
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2-[(dimethylamino)methyl]cyclohexan-1-one Chemical Properties,Usage,Production

Uses

2-(Bismethyl)aminomethylcyclohexanone is an intermediate in the synthesis of O-Desmethyl Tramadol Hydrochloride (D294750), an optically active metabolite of Tramadol.

Synthesis Reference(s)

Journal of the American Chemical Society, 98, p. 6715, 1976 DOI: 10.1021/ja00437a058
Synthetic Communications, 14, p. 585, 1984 DOI: 10.1080/00397918408059581

2-[(dimethylamino)methyl]cyclohexan-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[(dimethylamino)methyl]cyclohexan-1-one Suppliers

Canada 1 China 58 France 1 Germany 1 India 5 Switzerland 1 Ukraine 1 United Kingdom 2 United States 5 Global 75
Achemica
Tel
--
Fax
--
Email
contact@achemica.com
Country
Switzerland
ProdList
6155
Advantage
50

15409-60-6, 2-[(dimethylamino)methyl]cyclohexan-1-oneRelated Search:

2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride 2-[(dimethylamino)methyl]cyclohexan-1-one (3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE 2-(PIPERIDYLMETHYL)-1-CYCLOHEXANONE HYDROCHLORIDE 2-[(DIETHYLAMINO)METHYL]CYCLOHEXANONE HYDROCHLORIDE 2-[(N,N-DIBENZYLAMINO)METHYL]CYCLOHEXANONE, HYDROCHLORIDE 2-(Bistrideuteromethyl)amniomethylcyclohexanone-D6 AKOS BBS-00000410 Pimeclone SPECS AF-399/25108033 N,N-Dimethyl-2-aminomethyl-4,4-diphenylcyclohexanone hydrochloride AKOS BC-0774 SPIRO[5,5-DIMETHYL-1,3-CYCLOHEXANEDIONE-2,5'-(3'-PHENYL-2',3',4',4A',5',6'-HEXAHYDRO-1'H-PYRAZINO[1',2'-A']QUINOLINE)] RARECHEM AQ NN 0359 RARECHEM AQ NN 0358 SPIRO[5,5-DIMETHYL-1,3-CYCLOHEXANEDIONE-2,5'-(9'-CHLORO-3'-PHENYL-2',3',4',4A',5',6'-HEXAHYDRO-1'H-PYRAZINO[1',2'-A']QUINOLINE)] SPIRO[1,3-CYCLOHEXANEDIONE-2,5'-(3'-(2',3'-DIMETHYLPHENYL)-2',3',4',4A',5',6'-HEXAHYDRO-1'H-PYRAZINO[1,'2'-A']QUINOLINE)] SPIRO[5,5-DIMETHYL-1,3-CYCLOHEXANEDIONE-2,5'-(3'-BENZYL-2',3',4',4A',5',6'-HEXAHYDRO-1'H-PYRAZINO[1',2'-A']QUINOLINE)]

  • 2-[(dimethylamino)methyl]cyclohexan-1-one
  • 2-(Dimethylamino)methylcyclohexanone
  • 2-[(N,N-DIMETHYLAMINO)METHYL]-CYCLOHEXANONE HYDROCHLORIDE
  • Cyclohexanone,2-[(diMethylaMino)Methyl]-
  • 2-(BisMethyl)aMinoMethylcyclohexanone
  • 2-((DIMETHYLAMINO)METHYL)CYCLOHEXANONE(WXG01629)
  • dimethylaminomethyl cyclohexanone
  • Tramadol Impurity E (Y0000157)
  • 15409-60-6