ChemicalBook > CAS DataBase List > (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

Product Name
(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
CAS No.
5843-53-8
Chemical Name
(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
Synonyms
BA-7205;Rexigen;ClobenzorexHCl;Einecs 227-434-5;(S)-(+)-Clobenzorex Hydrochloride;N-(2-chlorobenzyl)-1-phenylpropan-2-amine hydrochloride;Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine;(2-chlorobenzyl)-(1-methyl-2-phenyl-ethyl)amine hydrochloride;N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine hydrochloride;(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
CBNumber
CB9928091
Molecular Formula
C16H19Cl2N
Formula Weight
296.23476
MOL File
5843-53-8.mol
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(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Property

Melting point:
182-183° (isopropanol)
alpha 
D20 +26.3° (water)
solubility 
Methanol (Slightly), Water (Slightly, Heated)
form 
Solid
color 
White to Off-White
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Safety

Toxicity
LD50 i.p. in mice: 103 mg/kg (Boissier et al.)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FC131572
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
250mg
Price
$57.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC131572
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
500mg
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
155683
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
0.500g
Price
$160
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC131572
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
1g
Price
$170
Updated
2021/12/16
Matrix Scientific
Product number
155683
Product name
N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
Packaging
1g
Price
$200
Updated
2021/12/16
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(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Asenlix,Aventis

Uses

The S-enantiomer of Clobenzorex (C583000), an anorexic.

Manufacturing Process

A solution of 21.0 g (0.15 mol) of 2-chlorobenzaldehyde in 100 ml of ethanol (95%) was added to a solution of 20.5 g (0.152 mol) of D-1-phenyl-2-aminopropane in 100 ml of ethanol (95%). After standing for 15 h at room temperature, the ethanol was driven off, and the oily residue was then distilled to yield 36.2 g (94%) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane, boiling point 142°-146°C/0.1 mm Hg.
To the solution of 36.0 g (0.14 mol) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane in 200 ml of dry methanol were added, in portions, 5.3 g (0.14 mol) of sodium borohydride. The mixture was stirred for 1 h at room
temperature, and refluxed for 1 h water (100 ml) was then added and the methanol was removed in vacuo. After acidifying carefully with dilute hydrochloric acid, the solution was made alkaline by dilute sodium hydroxide, and extracted with ether. 33.0 g (90%) of D-N-(1-phenyl-2-propyl)-2-
chlorobenzylamine, boiling point 132°-134°C/0.1 mm Hg, were obtained by distillation.

Therapeutic Function

Anorexic

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

5843-53-8, (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochlorideRelated Search:


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  • (2-chlorobenzyl)-(1-methyl-2-phenyl-ethyl)amine hydrochloride
  • N-(2-chlorobenzyl)-1-phenylpropan-2-amine hydrochloride
  • BA-7205
  • Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine
  • Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine [french]
  • Einecs 227-434-5
  • (S)-(+)-Clobenzorex Hydrochloride
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  • N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine hydrochloride
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  • Rexigen
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  • (2S)-N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine:hydrochloride
  • ClobenzorexHCl
  • (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride
  • 5843-53-8
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