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bamifylline hydrochloride

Product Name
bamifylline hydrochloride
CAS No.
20684-06-4
Chemical Name
bamifylline hydrochloride
Synonyms
AC-3810;Briofil;BAX2793Z;Trentadil;BAX 2793Z;BAX-2793Z;BAMIFYLLINE HCL;BAMIPHYLLINE HCL;BAMIPHYLLINE HCL (GMP);Bamiphyllinehydrochloride
CBNumber
CB9929568
Molecular Formula
C20H27N5O3.ClH
Formula Weight
421.926
MOL File
20684-06-4.mol
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bamifylline hydrochloride Property

Melting point:
185-186°
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Safety

Toxicity
LD50 in mice, rats (mg/kg): 246, 1139 orally; 89, 131 i.p.; 67, 65 i.v. (Georges)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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bamifylline hydrochloride Chemical Properties,Usage,Production

Originator

Bamifylline,ZYF Pharm Chemical

Uses

Bronchodilator.

Manufacturing Process

A mixture of 100 kg of 8-benzyltheophilline, 36 L of N-ethylethanolamine, 300 L of 1,2-dichlorethane and 71 kg of sodium carbonate was refluxed for 24 hours. Then 36 L of N-ethylethanolamine was added and the reaction mixture was refluxed. After cooling to the mixture was added the water and hydrochloric acid. The organic phase was extracted with hydrochloric acid. The acidic phase was neutralized with sodium carbonate and the 7-(N-ethyl-N-β- hydroxyethylaminoethyl)-8-benzyltheophilline was extracted with dichloromethane. The solvent was evaporated and the free base of 7-(N-ethyl- N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was dissolved in methanol. Hydrochloride of 7-(N-ethyl-N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was obtained by addition to the solution the hydrochloric acid; yield 81%, melting point 185-186°C.

Therapeutic Function

Bronchodilator, Coronary vasodilator

bamifylline hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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bamifylline hydrochloride Suppliers

China 12 Germany 2 India 5 Italy 1 United States 4 Global 24
Pharma Affiliates
Tel
--
Fax
--
Email
@pharmaffiliates.com
Country
India
ProdList
6754
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Medilink Pharmachem
Tel
--
Fax
--
Email
exports@medilinkpharma.com
Country
India
ProdList
424
Advantage
50
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View Lastest Price from bamifylline hydrochloride manufacturers

Anhui Ruihan Technology Co., Ltd
Product
bamifylline hydrochloride 20684-06-4
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-09-11

20684-06-4, bamifylline hydrochlorideRelated Search:

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