PALMITOYL CARNITINE Property

storage temp. 

2-8°C

solubility 

Soluble in DMSO

form 

liquid

optical activity

[α]/D -17±2°, c = 1 in methanol

BRN 

4152034

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

PALMITOYL CARNITINE Chemical Properties,Usage,Production

Uses

L-?Palmitoyl Carnitine is used as a diagnostic agent in the investigation of drug toxicity with respect to the liver. Acts as a biomarker in the study of metabolism in metabolic diseases.

Definition

ChEBI: An O-acyl-L-carnitine in which the acyl group is specified as palmitoyl (hexadecanoyl).

General Description

Palmitoyl-L-carnitine (PLC) belongs to the class of long chain acylcarnitine compounds. It is an acyl-chain ester, which can be obtained from L-carnitine via acylcarnitine family transferase. PLC is reported to be used for the phospholipid reacylation in erythrocyte membrane ghosts.

Biochem/physiol Actions

L-Palmitoylcarnitine can change the activity of several enzymes and transporters, localized in the membrane and facilitates the transfer of long-chain fatty acids from cytoplasm into mitochondria during the oxidation of fatty acids. L-Palmitoylcarnitine accumulates in ischemic myocardium and potentially contribute to myocardial damage through alterations in membrane molecular dynamics.