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2-amino-N,N-dimethylacetamide

Product Name
2-amino-N,N-dimethylacetamide
CAS No.
1857-19-8
Chemical Name
2-amino-N,N-dimethylacetamide
Synonyms
A80236;Glycine dimethylamide, 97%;N~1~,N~1~-dimethylglycinamide;N,N-Dimethyl-2-aminoacetamide;2-Amino-N,N-dimethylacetamide;1,1-diMethylurea hydrochloride;AcetaMide, 2-aMino-N,N-diMethyl;2-diazenyl-N,N-dimethylacetamide;2-aMino-N,N-diMethylacetaMide hcl;N~1~,N~1~-dimethylglycinamide 1HCl
CBNumber
CB9970898
Molecular Formula
C4H10N2O
Formula Weight
102.14
MOL File
1857-19-8.mol
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2-amino-N,N-dimethylacetamide Property

Boiling point:
60 °C(Press: 0.8 Torr)
Density 
0.995±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
8.46±0.10(Predicted)
form 
liquid
color 
Colorless
Sensitive 
Air Sensitive
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Safety

HazardClass 
8
HS Code 
2922498590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC
Product number
A597200
Product name
2-Amino-N,N-dimethylacetamide
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
A597200
Product name
2-Amino-N,N-dimethylacetamide
Packaging
250mg
Price
$70
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA64051
Product name
2-Amino-N,N-dimethylacetamide
Packaging
250mg
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA64051
Product name
2-Amino-N,N-dimethylacetamide
Packaging
500mg
Price
$125
Updated
2021/12/16
AK Scientific
Product number
W4015
Product name
2-Amino-N,N-dimethylacetamide
Packaging
1g
Price
$144
Updated
2021/12/16
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2-amino-N,N-dimethylacetamide Chemical Properties,Usage,Production

Uses

Glycine dimethylamide is used as pharmaceutical intermediate.

Synthesis

167303-60-8

1857-19-8

GENERAL STEPS: This procedure was used for the synthesis of 2-amino-N,N-dimethylacetamide (compound 11a). To a solution of benzyl (2-(dimethylamino)-2-oxoethyl)carbamate (compound 10a, 170 mg, 0.77 mmol) in methanol (10 mL) was added 10% Pd/C catalyst. The reaction was hydrogenated at room temperature and atmospheric pressure for 3 hours. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the filtrate was concentrated and dried to give 2-amino-N,N-dimethylacetamide as an oily product. The reaction process was monitored by TLC. Due to product stability considerations, the resulting amine was used directly in the subsequent reaction. The yield was 97%.

References

[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 3, p. 1285 - 1297
[2] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 16, p. 2715 - 2718
[3] Chemical Communications, 2016, vol. 52, # 43, p. 7043 - 7046

2-amino-N,N-dimethylacetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-amino-N,N-dimethylacetamide Suppliers

UkrOrgSynthesis Ltd.
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
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View Lastest Price from 2-amino-N,N-dimethylacetamide manufacturers

Career Henan Chemical Co
Product
2-amino-N,N-dimethylacetamide 1857-19-8
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
85.0-99.8%
Supply Ability
20tons
Release date
2020-01-08

1857-19-8, 2-amino-N,N-dimethylacetamideRelated Search:


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  • 2-Amino-N,N-dimethylacetamide
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