NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE
NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE Basic information
- Product Name:
- NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE
- Synonyms:
-
- NZ-419 84210-26-4
- NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE
- 5-hydroxy-1-methylhydantoin
- 5-hydroxy-1-methylimidazolidine-2,4-dione
- 1-methyl-5-hydroxy-imidazoline-2,4-dione
- 2,4-Imidazolidinedione, 5-hydroxy-1-methyl-
- HD 003
- HD003
- CAS:
- 84210-26-4
- MF:
- C4H6N2O3
- MW:
- 130.1
- Mol File:
- 84210-26-4.mol
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NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE Chemical Properties
- storage temp.
- Storage temp. 2-8°C
- form
- Solid
- color
- White to off-white
- optical activity
- -1.3816°(C=1.0025g/100ml MEOH)
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NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE Usage And Synthesis
Uses
NZ 419 (5-Hydroxy-1-methylhydantoin) is a metabolite of creatinine and an antioxidant with oral activity, which has the ability to scavenge hydroxyl radicals (?OH). NZ 419 can inhibit the progression of chronic kidney disease (CKD) in rats[1].
References
[1] Ienaga K, et al. Creatinine and HMH (5-hydroxy-1-methylhydantoin, NZ-419) as intrinsic hydroxyl radical scavengers. Drug Discov Ther. 2011;5(4):162-175. DOI:10.5582/ddt.2011.v5.4.162
NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONESupplier
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