SDZWAG994 Chemical Properties

storage temp. 

Desiccate at +4°C

solubility 

Soluble to 100 mM in 1.1eq. NaOH and to 100 mM in DMSO

form 

Powder

SDZWAG994 Usage And Synthesis

Uses

Adenosine receptors are potential therapeutic targets for cerebral and cardiac ischaemic diseases, sleep disorders, immune and inflammatory disorders and cancer. N-Cyclohexyl-2''-O-methyladenosine is an inhibitor of adenosine deaminase-induced lipolysis and a selective adenosine A1-R agonist.

Biological Activity

Potent and selective A 1 adenosine receptor agonist (K i values are 23, > 10000 and 25000 nM for A 1 , A 2A and A 2B receptors respectively). Causes a sustained fall in blood pressure and heart rate in spontaneous hypertensive rats and inhibits adenosine deaminase-stimulated lipolysis in rat adipocytes (K i = 8 nM).

storage

Desiccate at +4°C

SDZWAG994(130714-47-5)Related Product Information

• 2'-O-Methyladenosine
• SDZWAG994
• 6-N-HEXYLAMINOPURINE
• N6-CYCLOHEXYLADENOSINE