5'-Amino-2'-hydroxyacetophenone Chemical Properties

Melting point:

121–122°C

Boiling point:

335.4±27.0 °C(Predicted)

Density 

1.242±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

10.42±0.18(Predicted)

Safety Information

HS Code 

2914500090

5'-Amino-2'-hydroxyacetophenone Usage And Synthesis

Uses

1-(5-Amino-2-hydroxyphenyl)ethanone is used in the preparation of alkylated flavonoid compounds for use as therapeutic antioxidants. It is also used to synthesize spiro[chromanone-piperidine]s as acetyl-CoA carboxylase inhibitors.

Preparation

Also obtained by refluxing a suspension of N-(3-acetyl-4- hydroxyphenyl)acetamide in 15% hydrochloric acid for 40 min (84%).

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