5-Bromo-thiophene-2-carboxylic acid methyl ester Chemical Properties

Melting point:

87-88℃

Boiling point:

251.9±20.0 °C(Predicted)

Density 

1.662±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

Safety Information

HS Code 

2932990090

5-Bromo-thiophene-2-carboxylic acid methyl ester Usage And Synthesis

Uses

Methyl 5-Bromo-2-thiophenecarboxylate is used as a reagent in the synthesis of trisubstituted isoxazole derivatives which are novel nonsteroidal antagonists of Farnesoid X Receptor (FXR). FXR plays an important role in regulation of cholesterol, lipid and glucose metabolism.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 35, p. 1109, 1992 DOI: 10.1021/jm00084a016

5-Bromo-thiophene-2-carboxylic acid methyl ester(62224-19-5)Related Product Information

• Dibenzothiophene
• 2-Thiophenecarboxylic acid, 5-bromo-4-fluoro-, methyl ester
• 2-Thiophenecarboxylic acid, 4,5-dibromo-3-fluoro-, methyl ester
• METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE
• RARECHEM AL BI 0455
• SPECS AI-942/25034100
• METHYL 5-BROMO-3-METHYLTHIOPHENE-2-CARBOXYLATE
• METHYL 4,5-DIBROMO-3-METHOXYTHIOPHENE-2-CARBOXYLATE
• Ethyl 5-bromothiophene-2-carboxylate
• methyl 5-bromo-4-(chlorosulfonyl)thiophene-2-carboxylate
• METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE
• 5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester
• 5-Bromo-thiophene-2-carboxylic acid methyl ester
• METHYL4,5-DIBROMOTHIOPHENE-2-CARBOXYLATE