Transcainide CAS#: 88296-62-2

Transcainide Basic information

Product Name:

Transcainide

Synonyms:

Transcainide
R-54718
rel-(1R*)-2β*-[4-[(2,6-Dimethylphenyl)carbamoyl]-4-(dimethylamino)piperidino]1β*-cyclohexanol
4-(dimethylamino)-N-(2,6-dimethylphenyl)-1-[(1R,2R)-2-hydroxycyclohexyl]piperidine-4-carboxamide
4-Piperidinecarboxamide, 4-(dimethylamino)-N-(2,6-dimethylphenyl)-1-[(1R,2R)-2-hydroxycyclohexyl]-,rel-

CAS:

88296-62-2

MF:

C22H35N3O2

MW:

373.538

Mol File:

88296-62-2.mol

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Transcainide Usage And Synthesis

Uses

Transcainide (R 54718) is an orally active antiarrhythmic agent[1].

References

[1] Zamponi GW, et al. Transcainide causes two modes of open-channel block with different voltage sensitivities in batrachotoxin-activated sodium channels. Biophys J. 1994 Sep;67(3):1028-39. doi: 10.1016/S0006-3495(94)80568-5. Erratum in: Biophys J 1995 Mar;68(3):1197. DOI:10.1016/S0006-3495(94)80568-5
[2] R Stroobandt, Evaluation of the efficacy and tolerance of the antiarrhythmic agent transcainide (R 54718). Eur J Clin Pharmacol. 1987;32(5):449-56. DOI:10.1007/BF00637668

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