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6-Mercaptopurine disulfide

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6-Mercaptopurine disulfide Basic information

Product Name:
6-Mercaptopurine disulfide
Synonyms:
  • 6,6DITHIOBISPURINE
  • Azathioprine impurity C
  • 6-(7H-purin-6-yldisulfanyl)-7H-purine
  • Mercaptopurine Impurity 2
  • 9H-Purine, 6,6'-dithiodi-
  • Mercaptopurine Impurity 2 (Mercaptopurine EP Impurity D)
  • 6,6′-Dithiodi-9H-purine
  • 1,2-di(7H-purin-6-yl)disulfane
CAS:
49808-20-0
MF:
C10H6N8S2
MW:
302.34
Mol File:
49808-20-0.mol
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6-Mercaptopurine disulfide Chemical Properties

Melting point:
>219°C (dec.)
Boiling point:
447.2±55.0 °C(Predicted)
Density 
2.06±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Aqueous Base (Slightly, Heated), DMSO (Slightly)
pka
8.08±0.20(Predicted)
form 
Solid
color 
Yellow to Dark Yellow
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6-Mercaptopurine disulfide Usage And Synthesis

Uses

6-Mercaptopurine Disulfide is an impurity of 6-Mercaptopurine (M225450, monohydrate) which is an immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.

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