1,2-DIMYRISTOYL-SN-GLYCEROL Chemical Properties

Melting point:

57-61 °C

Boiling point:

577.2±17.0 °C(Predicted)

Density 

0.940±0.06 g/cm3(Predicted)

storage temp. 

-15°C

solubility 

DMF: 20 mg/ml; DMSO: 7 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.25 mg/ml

pka

13.69±0.10(Predicted)

form 

powder

color 

White to off-white

biological source

synthetic (organic)

BRN 

1808871

InChI

InChI=1S/C31H60O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-30(33)35-28-29(27-32)36-31(34)26-24-22-20-18-16-14-12-10-8-6-4-2/h29,32H,3-28H2,1-2H3/t29-/m0/s1

InChIKey

JFBCSFJKETUREV-LJAQVGFWSA-N

SMILES

[C@H](OC(=O)CCCCCCCCCCCCC)(CO)COC(=O)CCCCCCCCCCCCC

1,2-DIMYRISTOYL-SN-GLYCEROL Usage And Synthesis

Description

1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is a saturated diacylglycerol (DAG) with myristic acid (14:0) side-chains attached at both the sn-1 and sn-2 positions. Most saturated DAGs, including 1,2-DMG, are weak second messengers for the activation of the PKC.

Chemical Properties

White powder with lumps

Uses

1,2-Dimyristoyl-sn-glycerol is a saturated diacylglycerol (DAG). It is a possible weak second messenger for the activation of the PKC.

Uses

1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is a saturated diacylglycerol (DAG) with myristic acid (14:0) side-chains attached at both the sn-1 and sn-2 positions. Most saturated DAGs, including 1,2-DMG, are weak second messengers for the activation of the PKC.[Cayman Chemical]

Definition

ChEBI: 1,2-ditetradecanoyl-sn-glycerol is a 1,2-diacyl-sn-glycerol in which both acyl groups are tetradecanoyl (myristoyl). It is a 1,2-diacyl-sn-glycerol and a diacylglycerol 28:0. It is functionally related to a tetradecanoic acid.

References

[1] P SáNCHEZ-PI?ERA. A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.[J]. Biochemical Journal, 1999, 337 ( Pt 3): 387-395.

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