Betulin-3-acetate
Betulin-3-acetate Basic information
- Product Name:
- Betulin-3-acetate
- Synonyms:
-
- Betulin-3-acetate
- 3β-Acetoxylupa-20(29)-ene-28-ol
- Betulin monoacetate
- Lup-20(29)-ene-3β,28-diol 3-acetate
- Lupane-20(29)-ene-3β,28-diol 3-acetate
- Betulin 3-O-acetate, 97%, Semi-Synthetic
- Lup-20(29)-ene-3,28-diol, 3-acetate, (3β)-
- 3-Acetyl Betulin
- CAS:
- 27570-20-3
- MF:
- C32H52O3
- MW:
- 484.75
- Mol File:
- 27570-20-3.mol
More
Less
Betulin-3-acetate Chemical Properties
- storage temp.
- -20°C
- solubility
- DMF: 5 mg/ml
- form
- A crystalline solid
More
Less
Betulin-3-acetate Usage And Synthesis
Biological Activity
3-Acetyl betulin is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1,2 It is an intermediate in the synthesis of various lupane and germanicane triterpenes and saponins with anticancer activity.
References
1.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007) 2.B?benek, E., Kadela-Tomanek, M., Chrobak, E., et al.Novel triazoles of 3-acetylbetulin and betulone as anticancer agentsMed. Chem. Res.27(9)2051-2061(2018)