ANTI-TRAIL
ANTI-TRAIL Basic information
- Product Name:
- ANTI-TRAIL
- Synonyms:
-
- ANTI-HUMAN TRAIL/APO2L POLYCLONAL ANTIBODY
- ANTI-HUMAN TRAIL, CLONE B-S23, MONOCLONAL ANTIBODY
- ANTI-HUMAN TRAIL, CLONE B-T24, MONOCLONAL ANTIBODY
- MONOCLONAL ANTIBODY TO TRAIL (HUMAN) (2E5)
- MONOCLONAL ANTIBODY TO TRAIL (HUMAN) (5D5)
- MONOCLONAL ANTIBODY TO TRAIL (HUMAN) (HS501)
- MONOCLONAL ANTIBODY TO TRAIL (HUMAN) (LLL6F)
- MONOCLONAL ANTIBODY TO TRAIL (HUMAN) (VI10E)
- MW:
- 0
- Mol File:
- Mol File
ANTI-TRAIL Chemical Properties
- storage temp.
- -20°C
- form
- lyophilized powder
- biological source
- mouse
MSDS
- Language:English Provider:SigmaAldrich
ANTI-TRAIL Usage And Synthesis
Uses
Monoclonal Anti-TRAIL antibody produced in mouse has been used in fluorescence-activated cell sorting (FACS).
General Description
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) cytokine family. This ligand is a type II transmembrane protein that contains a short cytoplasmic N-terminal domain and a long C-terminal extracellular receptor-binding domain. TRAIL is highly expressed in immune system cells. The TRAIL gene is located on the human chromosome at 3q26.31.
Biochem/physiol Actions
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) binds to TRAIL 1 & 2 receptors and induces apoptosis. This ligand is involved in the homeostasis of T-cells and natural killer (NK) cells. TRAIL also aids in the T-cell-mediated killing of virus-infected cells and oncogenic transformed cells.