2'-HYDROXY-2,4,4',5,6'-PENTAMETHOXYCHALCONE Chemical Properties

Boiling point:

586.1±50.0 °C(Predicted)

Density 

1.214±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO: 2mg/mL, clear (warmed)

pka

6.79±0.40(Predicted)

form 

powder

color 

yellow to orange

2'-HYDROXY-2,4,4',5,6'-PENTAMETHOXYCHALCONE Usage And Synthesis

Definition

ChEBI: Rubone is a member of chalcones.

Biological Activity

Rubone has strong anticancer activity. Rubone and paclitaxel (PTX) combination therapy retarded cancer cell growth, migration and cancer stem-like cells (CSC) population growth.', 'Rubone is a miR34a modulator th at specifically restores miR34a in hepatocellular carcinoma cells with wild-type or mutated p53. Rubone potently inhibits growth of hepatocellular carcinoma in a mouse xenograft model. Rubone does not effect the growth of nontumorigenic human hepatocytes.', 'Rubone is a miR34a modulator th at specifically restores miR34a in hepatocellular carcinoma cells.

2'-HYDROXY-2,4,4',5,6'-PENTAMETHOXYCHALCONE(73694-15-2)Related Product Information

• 2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE
• 2'-HYDROXY-4,4',6'-TRIMETHOXYCHALCONE
• 2',4-DIHYDROXY-4',6'-DIMETHOXYCHALCONE
• 2'-HYDROXY-2,4,4',5,6'-PENTAMETHOXYCHALCONE
• 2,2',4'-TRIHYDROXYCHALCONE
• 4,2'-DIHYDROXY-3,4',6'-TRIMETHOXYCHALCONE
• 4,4'-DIHYDROXY-2-METHOXYCHALCONE
• 2,4,4'-TRIHYDROXY BENZALACETOPHENONE
• metochalcone
• 2-HYDROXY-2',4',6'-TRIMETHOXYCHALCONE
• 2,4,4'-TRIMETHOXYCHALCONE
• alpha-Asarone