Basic information Safety Supplier Related

(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate

Basic information Safety Supplier Related

(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate Basic information

Product Name:
(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate
Synonyms:
  • (1S)-(+)-MENTHYL GLYOXYLATE HYDRATE
  • Glyoxylic acid (1S)-menthyl ester hydrate
  • L)-Menthyl glyoxylate monohydrate
  • (S)-(+)-MENTHYL GLYOXYLATE HYDRATE
  • (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate
  • 2,2-Dihydroxyacetic acid (-)-menthyl ester
  • L-Menthyl glyoxylate hydrate
  • L-MGH
CAS:
111969-64-3
MF:
C12H22O4
MW:
230.3
EINECS:
416-810-6
Mol File:
111969-64-3.mol
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(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate Chemical Properties

Melting point:
76-78°C
Boiling point:
320°C
Density 
1.09
Flash point:
113°C
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
10.79±0.41(Predicted)
color 
White to Almost white
Water Solubility 
400g/L
Sensitive 
Air Sensitive
BRN 
4905777
CAS DataBase Reference
111969-64-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
51/53-48/22-41
Safety Statements 
61-36/39-26-22
RIDADR 
3077
HazardClass 
9
PackingGroup 
III
HS Code 
2918199890

MSDS

  • Language:English Provider:ALFA
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(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate Usage And Synthesis

Chemical Properties

Class white particles

Uses

L-Menthyl 2,2-Dihydroxyacetate is used as a reagent in the synthesis of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor used for the treatment of chronic hepatitis B. L-Menthyl 2,2-Dihydroxyacetate is also used as a reagent in the synthesis of 4-acetoxy-3-hydroxyethylazetidin-2-one, a key intermediate for the preparation of penem and carbapenem antibiotics.

(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetateSupplier

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