Basic information Safety Supplier Related

FR 139317

Basic information Safety Supplier Related

FR 139317 Basic information

Product Name:
FR 139317
Synonyms:
  • FR 139317
  • (HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-D-(1-ME)-TRP-DPAL
  • (HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-DTRP(ME)-D-ALA(2-PYRIDYL)-OH
  • 2-((1-(Hexahydro-1H-azepinyl)carbonyl)amino-4-methylpentanoyl)-3-(-(1-methyl-1H-indolyl)propionyl)amino-3-(2-pyridyl)propionic acid
  • D-Alanine, N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl-1-methyl-D-tryptophyl-3-(2-pyridinyl)-
  • D-Alanine, N-(N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-3-(2-pyridinyl)-
  • (2R)-2-[[(2R)-2-[[(2S)-2-(AZEPANE-1-CARBONYLAMINO)-4-METHYLPENTANOYL]AMINO]-3-(1-METHYLINDOL-3-YL)PROPANOYL]AMINO]-3-PYRIDIN-2-YLPROPANOIC ACID
  • FR139317,CID107810
CAS:
142375-60-8
MF:
C33H44N6O5
MW:
604.74
Mol File:
142375-60-8.mol
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FR 139317 Chemical Properties

Boiling point:
943.9±65.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at +4°C
solubility 
Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
form 
Powder
pka
2.68±0.10(Predicted)
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FR 139317 Usage And Synthesis

Uses

FR 139317 is a novel, potent endothelin ETA receptor antagonist.

Biological Activity

A highly potent and selective ET A endothelin receptor antagonist (K i values are 1 nM and 7.3 μ M at ET A and ET B subtypes respectively). Active in vivo .

FR 139317Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Email
ymbetter@glbiochem.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
EMMX Biotechnology LLC
Tel
888-539-0666
Email
info@emmx.com
Nanjing Peptide Biotech Ltd.
Tel
025-025-58361106-805-805 13082558573
Email
liugang@njpeptide.com