NERIIFOLIN
NERIIFOLIN Basic information
- Product Name:
- NERIIFOLIN
- Synonyms:
-
- 14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside), 3-([6-Deoxy-3-O-methyl-α-L-glucopyranosyl]oxy)-14-hydroxy-5β-card-20(22)-enolide]
- NERIIFOLIN
- digitoxigenin+thevetose
- xy)-14-hydroxy-
- (3-beta,5-beta)-3-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- (5beta)-3beta-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- (17R)-3β-(3-O-Methyl-6-deoxy-α-L-glucopyranosyloxy)-14-hydroxy-5β,14β-carda-20(22)-enolide
- 17α-Neriifolin
- CAS:
- 466-07-9
- MF:
- C30H46O8
- MW:
- 534.68
- EINECS:
- 207-372-5
- Mol File:
- 466-07-9.mol
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NERIIFOLIN Chemical Properties
- Melting point:
- 218-225°C
- alpha
- D23 -50.2° (CH3OH)
- storage temp.
- 2-8°C
- solubility
- Chloroform(Slightly), DMSO(Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- Pale Yellow
- biological source
- plant
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Safety Information
- Hazard Codes
- T+
- Risk Statements
- 26/27/28
- Safety Statements
- 22-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 1
- WGK Germany
- 3
- RTECS
- FH4906100
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NERIIFOLIN Usage And Synthesis
Uses
17β-neriifolin could be considered a candidate for the treatment of hepatocellular carcinoma. It can also work as an inhibitor of hERG channel trafficking.
Definition
ChEBI: A cardenolide glycoside that is digitoxigenin in which the hydroxy goup at position 3 has been converted to its (6-deoxy-3-O-methyl-alpha-L-glucopyranoside derivative. Found in the seeds of Cerbera odollamand in Thevetia ahouia and Thevitia neriifolia.
Biological Activity
Neriifolin has a role as a cardiotonic drug, a toxin and a neuroprotective agent.
NERIIFOLINSupplier
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
Chengdu Push Bio-Technology Co., Ltd.
- Tel
- 028-85370565-229 18080489829
- 3004654993@qq.com
Dideu Industries Group Limited
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
BioBioPha Co., Ltd.
- Tel
- 0871-65217109
- y.liu@mail.biobiopha.com