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4-(N,N-DIMETHYLAMINOCARBONYL)PHENYLBORONIC ACID

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4-(N,N-DIMETHYLAMINOCARBONYL)PHENYLBORONIC ACID Basic information

Product Name:
4-(N,N-DIMETHYLAMINOCARBONYL)PHENYLBORONIC ACID
Synonyms:
  • N,N-DIMETHYL 4-BORONOBENZAMIDE
  • 4-(N,N-DIMETHYLAMINOCARBONYL)BENZENE BORONIC ACID
  • 4-(N,N-DIMETHYLAMINOCARBONYL)PHENYLBORONIC ACID
  • 4-(N,N-DIMETHYLCARBAMOYL)PHENYLBORONIC ACID
  • 4-(DIMETHYLAMINO)-CARBONYL-BENZENEBORONIC ACID
  • 4-[(DIMETHYLAMINO)CARBONYL]PHENYLBORONIC ACID
  • 4-(DIMETHYLCARBAMOYL)PHENYLBORONIC ACID
  • 4-(N,N-DIMENTHYLAMINOCARBONY)PHENYLNORORNIC ACID
CAS:
405520-68-5
MF:
C9H12BNO3
MW:
193.01
Product Categories:
  • Boronate Ester
  • Potassium Trifluoroborate
  • Boronic Acids and Derivatives
  • Chemical Synthesis
  • Monosubstituted Aryl Boronic Acids
  • Organometallic Reagents
  • BORONICACID
  • blocks
  • BoronicAcids
  • Boronic acids
  • Boronic Acid
  • Aryl
  • Organoborons
  • Aryl Boronic Acids
Mol File:
405520-68-5.mol
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4-(N,N-DIMETHYLAMINOCARBONYL)PHENYLBORONIC ACID Chemical Properties

Melting point:
141-145 °C
Boiling point:
407.4±47.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
7.76±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
Water Solubility 
Slightly soluble in water.
InChIKey
QJYYVSIRDJVQJW-UHFFFAOYSA-N
CAS DataBase Reference
405520-68-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
1
Hazard Note 
Irritant/Keep Cold
HS Code 
2931900090
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4-(N,N-DIMETHYLAMINOCARBONYL)PHENYLBORONIC ACID Usage And Synthesis

Chemical Properties

White Crysstalline

Uses

4-(Dimethylcarbamoyl)benzeneboronic acid used in coupling reactions and as intermediates.

Uses

Reactant for preparation of:• ;Selective glucocorticoid receptor agonists1• ;(thienopyridine)carboxamides as checkpoint 1 kinase (CHK1) inhibitors2• ;[(pyrrolo[2,3-b]pyridinyl)methylene]hydroxybenzofuranones as ATP-competitive inhibitors of the mammalian target of rapamycin3• ;Pyrrolopyridines as inhibitors of insulin-like growth factor-1 receptor tyrosine kinase4Reactant for:• ;Copper-mediated N-arylation of quinazolinediones5

General Description

May contain varying amounts of anhydride

4-(N,N-DIMETHYLAMINOCARBONYL)PHENYLBORONIC ACIDSupplier

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