3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE
3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE Basic information
- Product Name:
- 3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE
- Synonyms:
-
- 3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE
- 2'-Deoxy-2'-fluoro-3',5'-di-O-acetyluridine
- 1-[4-acetyl-3-fluoro-4-hydroxy-5-(1-hydroxy-2-oxopropyl)-2-oxolanyl]pyrimidine-2,4-dione
- ((2R,3R,4R,5R)-3-Acetoxy-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl acetate
- Uridine, 2'-deoxy-2'-fluoro-, 3',5'-diacetate
- 3’,5’-diacetyl-2'-Fluoro-2'-deoxyuridine
- 2’-Deoxy-2’-fluoro-3’,5’-di-O-acetyluridine
- 3',5'-Diacetyl-2'-Deoxy-2'-Fluorouridine
- CAS:
- 10212-13-2
- MF:
- C13H15FN2O7
- MW:
- 330.27
- Mol File:
- 10212-13-2.mol
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3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE Chemical Properties
- Melting point:
- 174-177°C
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.39±0.10(Predicted)
- color
- White to Off-White
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3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE Usage And Synthesis
Uses
3′,5′-Di-O-acetyl-2′-deoxy-2′-fluorouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
References
[1] Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. DOI:10.1016/s0165-6147(99)01298-5
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