(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Chemical Properties

Boiling point:

534.4±50.0 °C(Predicted)

Density 

1.228

storage temp. 

2-8°C

solubility 

DMSO: ≥35mg/mL

pka

9.99±0.26(Predicted)

form 

powder

color 

white to tan

optical activity

[α]/D +50 to +60° (c=1, MeOH)

Safety Information

Hazard Codes 

T,N

Risk Statements 

25-36-50

Safety Statements 

26-45-61

RIDADR 

2811

WGK Germany 

3

HazardClass 

IRRITANT

PackingGroup 

Ⅲ

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Usage And Synthesis

Uses

Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC50 of 10 nM.

Uses

CP-101,606 has been used as a N-methyl-D-aspartate (NMDA)?receptor antagonist to study its role in recovery of spinal cord injuries.

brand name

Traxoprodil is INN.

General Description

CP-101,606 (Traxoprodil) is a substituted 4-phenylpiperidine and is localized in the fore brain neurons.

Biochem/physiol Actions

Traxoprodil (CP-101,606) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. It has been shown to be neuroprotective in animal models of brain injury and stroke.

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL(134234-12-1)Related Product Information

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• Butyl acetate
• Ethyl acetate
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• alpha-[1-(Butylmethylamino)ethyl]-benzyl alcohol
• 4-HYDROXY-1-PIPERIDINEETHANOL 96
• (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL