1-phenethylpiperidin-4-ol Chemical Properties

Melting point:

95.5-98.5℃

Boiling point:

341.9±22.0 °C(Predicted)

Density 

1.064±0.06 g/cm3(Predicted)

solubility 

Acetonitrile: Slightly soluble
Chloroform: Soluble
Water: Slightly soluble

pka

14.87±0.20(Predicted)

Safety Information

HS Code 

2933399990

1-phenethylpiperidin-4-ol Usage And Synthesis

Uses

1-Phenethyl-4-piperidinol it is used in preparation of 1-Pyrrolidinyl Indane derivatives as Histamine H3 receptor antagonists useful in treatment of diseases.

References

[1] SHANAZ M. TEJANI-BUTT . N-Substituted derivatives of 4-piperidinyl benzilate: Affinities for brain muscarinic acetylcholine receptors[J]. Life sciences, 1990, 47 10: Pages 841-848. DOI: 10.1016/0024-3205(90)90596-j
[2] O. PREZZAVENTO*. Design and Synthesis of New Bifunctional Sigma-1 Selective Ligands with Antioxidant Activity[J]. Journal of Medicinal Chemistry, 2013, 56 6: 2447-2455. DOI: 10.1021/jm3017893
[3] SHIMPEI WATANABE. In Vitro and In Vivo Metabolite Identification Studies for the New Synthetic Opioids Acetylfentanyl, Acrylfentanyl, Furanylfentanyl, and 4-Fluoro-Isobutyrylfentanyl.[J]. AAPS Journal, 2017, 19 4: 1102-1122. DOI: 10.1208/s12248-017-0070-z

1-phenethylpiperidin-4-ol(3518-76-1)Related Product Information

• fenspiride
• (+)-BUTACLAMOL HYDROCHLORIDE
• 1-phenethylpiperidin-4-ol
• (+/-)-BUTACLAMOL HCL
• (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL
• Fenspiride hydrochloride
• 1,3-dimethyl-7-[2-oxo-2-(2-oxo-8-phenethyl-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)ethyl]purine-2,6-dione
• (1-phenethyl-4-piperidyl) benzoate hydrochloride
• Propinetidine
• Pipradimadol
• Phenactropinium chloride
• Pipramadol
• Tolquinzole
• ALPHA-DIHYDROTETRABENAZINE
• (-)-BUTACLAMOL HYDROCHLORIDE
• BENZQUINAMIDE
• BETA-DIHYDROTETRABENAZINE, [2-3H]
• ALPHA-DIHYDROTETRABENAZINE, [2-3H]