Dehydroepiandrosterone acetate Chemical Properties

Melting point:

168-170 °C(lit.)

Boiling point:

407.89°C (rough estimate)

Density 

1.0998 (rough estimate)

vapor pressure 

0Pa at 20℃

refractive index 

1.5192 (estimate)

storage temp. 

Refrigerator

solubility 

Chloroform, DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Off-White

optical activity

[α]20/D +2.4°, c = 2 in ethanol

Water Solubility 

11.5mg/L(temperature not stated)

InChI

InChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3

InChIKey

NCMZQTLCXHGLOK-KJBVPOJVSA-N

SMILES

C[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r|

LogP

5.1 at 20℃

CAS DataBase Reference

853-23-6

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

BV8396810

MSDS

• Language:English Provider:SigmaAldrich

Dehydroepiandrosterone acetate Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

Menopausal syndrome

Uses

A metabolite of Dehydroepiandrosterone. This mammalian pro-hormone promotes brain and immune function

Definition

ChEBI: Prasterone acetate is a steroid ester.

Flammability and Explosibility

Not classified

Biological Activity

Dehydroepiandrosterone acetate (DHEA, Androstenolone) is a kind of dehydroepiandrosterone derivatives. DHEA is an endogenous steroid hormone, which is considered to be a natural product/dietary supplement with many proposed benefits to humans.

in vivo

Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.

Dehydroepiandrosterone acetate(853-23-6)Related Product Information

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