(S)-N-Fmoc-2-(2'-propylenyl)alanine
(S)-N-Fmoc-2-(2'-propylenyl)alanine Basic information
- Product Name:
- (S)-N-Fmoc-2-(2'-propylenyl)alanine
- Synonyms:
-
- (S)-N-Fmoc-2-(2'-propylenyl)alanine
- (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid
- (S)-N-Fmoc-alpha-allylalanine
- (S)-N-(9-Fluorenylmethylcarbamate)-2-(2'-propylenyl)alanine
- Fmoc-alpha-methyl-L-allylglycine
- (S)-N-FMOC-Α-ALLYLALANINE
- FMoc-α-Me-Gly(Allyl)-OH
- (S)-N-Fmoc-α-2-n-propenylalanine
- CAS:
- 288617-71-0
- MF:
- C21H21NO4
- MW:
- 351.4
- Product Categories:
-
- α-Methyl Amino Acids
- Mol File:
- 288617-71-0.mol
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(S)-N-Fmoc-2-(2'-propylenyl)alanine Chemical Properties
- Boiling point:
- 564.3±45.0 °C(Predicted)
- Density
- 1.224
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- form
- liquid
- pka
- 3.81±0.11(Predicted)
- color
- pale yellow
- InChIKey
- FNCSRFHDUZYOCR-NRFANRHFSA-N
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(S)-N-Fmoc-2-(2'-propylenyl)alanine Usage And Synthesis
Uses
Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.
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(S)-N-Fmoc-2-(2'-propylenyl)alanine(288617-71-0)Related Product Information
- α-Me-D-Gly(Pentenyl)-OtBu p-Nitrobenzoate
- Boc-α-Me-D-Gly(Allyl)-OEt
- (R)-alpha-Methylaspartic acid-4-tert-butyl ester, 98% ee, 98%
- FMoc-α-Me-D-Asp(OtBu)-OH
- (R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-2-METHYL-HEPT-6-ENOIC ACID
- α-Me-Gly(Pentenyl)-OtBu p-Nitrobenzoate
- (S)-alpha-Methylaspartic acid-4-tert-butyl ester, 98% ee
- (R)-N-Fmoc-2-(2'-propylenyl)alanine
- (S)-2-METHYLCYSTEINE HYDROCHLORIDE
- FMoc-α-Me-D-Asn-OH
- FMoc-α-Me-D-Pro-OH
- Fmoc-alpha-methyl-D-leucine
- (S)-N-FMoc-2-(5'-pentenyl)alanine
- (S)-N-FMoc-2-(6'-heptenyl)alanine
- (S)-(+)-2-AMINO-2-METHYLBUTANEDIOIC ACID
- FMoc-α-Me-Asn-OH
- (R)-2-METHYLCYSTEINE HYDROCHLORIDE
- (S)-2-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-2-METHYLHEPT-6-ENOIC ACID