(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL Chemical Properties

Melting point:

54-56 °C(lit.)

alpha 

21 +8.2° (c = 10 in ethanol)

Boiling point:

bp0.1 mm 138-139°

Flash point:

>230 °F

optical activity

[α]21/D +8.2°, c = 10 in ethanol

Merck 

13,2070

BRN 

2384178

EPA Substance Registry System

Benzeneethanol, ?-[(1R)-2-(dimethylamino)-1-methylethyl]-?-phenyl-, (?S)- (38345-66-3)

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL Usage And Synthesis

Uses

Reducing reagent in organic synthesis.

Purification Methods

Purify the hydrochloride by dissolving 1.5g in 13.5 mL of 5N HCl, heat to boiling and evaporate in a vacuum. Recrystallise the hydrochloride three times from MeOH/EtOAc giving m 189-190o, []D -33.7o (c 1, H2O) {enantiomer has +34.2o}. The hydrochloride in the minimum volume of water is basified with aqueous 5N NaOH and extracted with Et2O. The extract is dried (K2CO3) and evaporated, leaving a residue which is stored in a desiccator over solid KOH as a low melting solid. It can be recovered using these procedures from asymmetric reductions with LAH, and re-used. [Pohland & Sullivan J Am Chem Soc 77 3400 1955, Sullivan et al. J Org Chem 28 2483 1963, Beilstein 13 IV 2221.]

(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL(38345-66-3)Related Product Information

• 3-METHYL-2-BUTANOL
• (2R,3S)-(-)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL
• PROPOXYPHENE RELATED COMPOUND A (50 MG) (ALPHA-D-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL HYDROCHLORIDE)
• PROPOXYPHENE HYDROCHLORIDE
• (+/-)-PROPOXYPHENE-D11
• alpha-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol propionate ester
• (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL
• PROPOXYPHENE NAPSYLATE
• LABOTEST-BB LT00847282
• D-PROPOXYPHENE-D5 HCL (PROPIONYL-D5)