N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide
N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide Basic information
- Product Name:
- N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide
- Synonyms:
-
- N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide
- 3-[[(1R,2R)-2-(1-piperidinyl)cyclohexyl]aMino]-4-[[4-(trifluoroMethyl)phenyl]aMino]-3-Cyclobutene-1,2-dione
- Rawal Squaramide Organocatalyst
- N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N'-[4-(trifluoromethyl)phenyl]squaramide 95%
- 3-[[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]amino]-4-[[4- (trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione,99%e.e.
- 3-[[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee)
- 3-Cyclobutene-1,2-dione, 3-[[(1R,2R)-2-(1-piperidinyl)cyclohexyl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-
- 3-(((1R,2R)-2-(Piperidin-1-yl)cyclohexyl)amino)-4-((4-(trifluoromethyl)phenyl)amino)cyclobut-3-ene-1,2-dione
- CAS:
- 1211565-08-0
- MF:
- C22H26F3N3O2
- MW:
- 421.46
- Mol File:
- 1211565-08-0.mol
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N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide Chemical Properties
- Melting point:
- 250 °C (decomp)
- Boiling point:
- 497.4±55.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- pka
- 8.97±0.20(Predicted)
- optical activity
- [α]/D -42.0±2.0°, c = 1 in DMSO
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N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide Usage And Synthesis
Uses
It can act as a catalyst for the asymmetric tandem aza-Michael addition-protonation between 1-nitro cyclohexene and 4-methoxyaniline to form the corresponding α-arylamino-β-nitro cyclohexane in a 35:65 trans/cis mixture.
N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMideSupplier
Adamas Reagent, Ltd. Gold
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
Daicel Chiral Technologies (China)CO.,LTD
- Tel
- 021-50460086-9 15921403865
- han_yajun@dctc.daicel.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Shanghai Chiral bio-compound co., Ltd.
- Tel
- 021-5068 3667/17749785980/1029026415; 17749785980
- 1029026415@qq.com
LaaJoo
- Tel
- 021-60702684 18516024827
- huang.jiayi@sinocompound.com
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N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide(1211565-08-0)Related Product Information
- 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1R,2R)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione
- 3-[[(9R)-6'-Methoxycinchonan-9-yl]aMino]-4-[[4-(trifluoroMethyl)phenyl]aMino]-3-Cyclobutene-1,2-dione
- 3-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-4-[[4-(trifluoroMethyl)phenyl]aMino]-3-Cyclobutene-1,2-dione
- 3-[[(1S,2S)-2-aMinocyclohexyl]aMino]-4-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-3-Cyclobutene-1,2-dione
- 3-[[(8α,9S)-6'-Methoxycinchonan-9-yl]aMino]-4-[[4-(trifluoroMethyl)phenyl]aMino]-3-Cyclobutene-1,2-dione