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GW791343 HCl

Basic information Safety Supplier Related

GW791343 HCl Basic information

Product Name:
GW791343 HCl
Synonyms:
  • GW791343 (trihydrochloride)
  • 2-(3,4-difluorophenylamino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide trihydrochloride
  • GW 791343 TRIHYDROCHLORIDE; GW-791343 TRIHYDROCHLORIDE;
  • GW791343 3HCl
  • GW791343 HCl USP/EP/BP
  • 2-((3,4-difluorophenyl)amino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide hydrogen chloride
CAS:
309712-55-8
MF:
C20H27Cl3F2N4O
MW:
483.8103864
Product Categories:
  • Inhibitors
Mol File:
309712-55-8.mol
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GW791343 HCl Chemical Properties

storage temp. 
Store at -20°C
solubility 
Soluble to 100 mM in water and to 100 mM in DMSO
form 
Powder
CAS DataBase Reference
309712-55-8
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GW791343 HCl Usage And Synthesis

Uses

GW 791343 Trihydrochloride is a P2X7 receptor antagonist that acts as an allosteric inhibitor, exhibiting negative allosteric effects at the human P2X7 receptor and positive allosteric effects at the rat P2X7 receptor. P2X7 receptor is responsible for the presence of inflammatory cells, regulated by extracellular ATP.

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