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K-Ras G12C-IN-1

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K-Ras G12C-IN-1 Basic information

Product Name:
K-Ras G12C-IN-1
Synonyms:
  • K-Ras G12C-IN-1
  • 1-[4-[2-[4-chloro-5-(2-chlorophenyl)-2-methoxyanilino]acetyl]piperazin-1-yl]prop-2-en-1-one
  • 2-Propen-1-one, 1-[4-[2-[(2',6-dichloro-4-methoxy[1,1'-biphenyl]-3-yl)amino]acetyl]-1-piperazinyl]-
  • KRas G12CIN1,K Ras G12C IN 1,K-Ras G-12C-IN-1
CAS:
1629265-17-3
MF:
C22H23Cl2N3O3
MW:
448.34
Mol File:
1629265-17-3.mol
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K-Ras G12C-IN-1 Chemical Properties

Boiling point:
676.3±55.0 °C(Predicted)
Density 
1.319±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: ≥ 40 mg/mL (89.22 mM)
form 
Powder
pka
2.55±0.50(Predicted)
color 
White to off-white
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K-Ras G12C-IN-1 Usage And Synthesis

Uses

K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1. IC50 value: Target: K-ras G12C inhibitor

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