ChemicalBook > Product Catalog > Pharmaceutical intermediates > Bulk Drug Intermediates > 5-Chloromethyl-2H-1,2,4-triazolin-3-one
5-Chloromethyl-2H-1,2,4-triazolin-3-one
5-Chloromethyl-2H-1,2,4-triazolin-3-one Basic information
- Product Name:
- 5-Chloromethyl-2H-1,2,4-triazolin-3-one
- Synonyms:
-
- 5-CHLOROMETHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE
- 3-Chloromethyl-1,2,4-triazol-5-one
- 3-Chloromethyl-1,2,4-triazolin-5-one
- 3-(chloromethyl)-1H-1,2,4-triazol-5(4H)-one
- 3-(chloroMethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one
- 5-(CHLOORMETHYL)-1,2-DIHYDRO-3H-1,2,4-TRIAZOOL-3-ON
- 5-Chloromethyl-2,4-Dithydro-[1,2,4]Triazol-3-One
- Aprepitant Impurity 51
- CAS:
- 252742-72-6
- MF:
- C3H4ClN3O
- MW:
- 133.54
- EINECS:
- 607-678-2
- Product Categories:
-
- pharmacetical
- Mol File:
- 252742-72-6.mol
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5-Chloromethyl-2H-1,2,4-triazolin-3-one Chemical Properties
- Melting point:
- 199°C(lit.)
- Density
- 1.83±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 7.46±0.20(Predicted)
- color
- White to Almost white
- CAS DataBase Reference
- 252742-72-6
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5-Chloromethyl-2H-1,2,4-triazolin-3-one Usage And Synthesis
Chemical Properties
White to Almost white powder to crystal
Uses
5-Chloromethyl-2H-1,2,4-triazolin-3-one is an intermediate used in the synthesis of Aprepitant (A729800) and Fosaprepitant, used as antiemetic drugs.
Application
3-Chloromethyl-1,2,4-triazolin-5-one is an intermediate in organic synthesis and pharmaceutical intermediate, which can be used in laboratory R&D synthesis process and chemical biological R&D process.
Hazard
5-Chloromethyl-2H-1,2,4-triazolin-3-one is a hazardous chemical that is corrosive to metals, irritating to the eyes and skin, and may cause respiratory irritation.
5-Chloromethyl-2H-1,2,4-triazolin-3-oneSupplier
Alchemist-pharm chemical Technology Co. Ltd. Gold
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Viwit Pharmaceutical Co., Ltd. Gold
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- 021-50790412
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