HNE Chemical Properties

Boiling point:

125-127 °C(Press: 2 Torr)

Density 

0.941±0.06 g/cm3(Predicted)

storage temp. 

-70°C

solubility 

DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1 mg/ml

pka

13.31±0.20(Predicted)

form 

Colorless oil.

color 

Colorless to light yellow

CAS DataBase Reference

75899-68-2(CAS DataBase Reference)

HNE Usage And Synthesis

Uses

4-Hydroxynonenal is an irreversible inhibitor of Na+/K+-ATPase activity.

Uses

HNE is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid. 4-hydroxy Nonenal is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. HNE inhibits pro-oxidant-induced Ca²⁺ release from mitochondria at 10-50 μM.[Cayman Chemical]

Definition

ChEBI: 4-hydroxynon-2-enal is an enal consisting of non-2-ene having an oxo group at the 1-position and a hydroxy group at the 4-position. It has a role as a human metabolite. It is a hydroxyaldehyde, an enal and a 4-hydroxynonenal.

HNE(75899-68-2)Related Product Information

• Titanium tetrachloride
• Glutathione
• 4-hydroxy Nonenal-d3
• (E)-4-HYDROXY-2-NONENAL,TRANS-4-HYDROXY-2-NONENAL
• TRANS-4-HYDROXY-2-NONENAL-5,5,6,6,7,7,8,8,9,9,9-D11 DIMETHYL ACETAL
• (E)-4-HYDROXYNONENAL-DIMETHYLACETAL,(E)-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA,(E)-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA,HNE-DA,HNE-DMA
• (E)-4-HYDROXYNONENAL, >85%
• HNE INHIBITOR
• ANTI-HNE FLUOROPHORE
• TAC, CD70, CD27 Ligand, Clone: HNE.51, Mab anti-Human, FITC
• ANTI-HNE PAB,ANTISERUM TO (E)-4-HYDROXYNONENAL
• 4-Hydroxynonenal conj. BSA Purified
• ANTI-(E)-4-HYDROXYNONENAL,ANTI-HNE,ANTI-4-HYDROXY-2-NONENAL
• 4R-HYDROXY-2-NONENAL
• ANTI-HNE-MICHAEL ADDUCTS, REDUCED,ANTI-HNE-MICHAEL ADDUCTS, REDUCED (RABBIT),ANTI-HNE-MICHAEL ADDUCTS, REDUCED RABBIT PAB
• 4S-HYDROXY-2-NONENAL
• TAC, CD70, CD27 Ligand, Clone: HNE.51, Mab anti-Human
• HNE (4-Hydroxy-2-nonenal),HNE (4-Hydroxy-2-nonenal)