Anti-HSU93850
Anti-HSU93850 Basic information
- Product Name:
- Anti-HSU93850
- Synonyms:
-
- Anti-EEF2K (73-85) antibody produced in rabbit
- Anti-EEF2K (N-term) antibody produced in rabbit
- Anti-EEF2K (C-term) antibody produced in rabbit
- Anti-EEF2K (176-190) antibody produced in rabbit
- Anti-EEF-2K
- Anti-Elongation factor-2 kinase
- Anti-HSU93850
- Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
- MW:
- 0
- Mol File:
- Mol File
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Anti-HSU93850 Chemical Properties
- storage temp.
- -20°C
- form
- buffered aqueous solution
- biological source
- rabbit
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Anti-HSU93850 Usage And Synthesis
Uses
Eukaryotic elongation factor 2 kinase (eEF2k) phosphorylates and inactivates eEF2, thereby inhibiting peptide-chain elongation. eEF2k, which is Ca2+ and calmodulin dependent, can be activated by PKA in response to stress-induced elevation of cAMP levels. eEF2k expression is also modulated by a wide range of stimuli that promote cell growth and protein synthesis. Phosphorylation of eEF2k by p90RSK and p70 S6 kinase at Ser366 or by SAPK4/p38d at Ser359, inactivates eEF2k, which facilitates the dephosphorylation of eEF2, and thus promotes translation.