5-METHOXYQUINOLIN-8-AMINE Chemical Properties

Melting point:

90-95°C

Boiling point:

355.7±27.0 °C(Predicted)

Density 

1.217±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

form 

powder

pka

3.98±0.12(Predicted)

5-METHOXYQUINOLIN-8-AMINE Usage And Synthesis

Uses

The Chen auxiliary was reported to be an effective directing group in the synthesis of pyrrolidones from assisting in the activation of C(sp³)-H bonds and can be readily installed through amide bond formation and removed through mild conditions using CAN at room temperature.

General Description

8-Amino-5-methoxyquinoline is a substituted quinoline derivative that can be prepared using 5-chloro-2-nitroaniline as a starting material. It can act as an easily removable directing group and also mediate C-H activation. These properties have been useful for synthesizing isomeric dibenzoxazepinones and complex pyrrolidinones from compounds containing 8-amino-5-methoxyquinoline moiety.

5-METHOXYQUINOLIN-8-AMINE(30465-68-0)Related Product Information

• Quinoline, 5-methoxy-8-nitro-
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• 5-METHOXYQUINOLINE
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• SQI-ET SODIUM FORM