Basic information Safety Supplier Related

5-ALPHA-PREGNANE

Basic information Safety Supplier Related

5-ALPHA-PREGNANE Basic information

Product Name:
5-ALPHA-PREGNANE
Synonyms:
  • ALLOPREGNANE
  • 5α-Pregnane
  • Pregnane
  • Pregnane, (5alpha)-
  • 5-ALPHA-PREGNANE
  • 5ALPHA-PREGNAN
  • Pregnane, (5α)-
  • 5α(H)-Pregnane in isooctane
CAS:
641-85-0
MF:
C21H36
MW:
288.51
EINECS:
211-378-3
Mol File:
641-85-0.mol
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5-ALPHA-PREGNANE Chemical Properties

Melting point:
84-85°
alpha 
D19 +18.4° (c = 1.69 in chloroform)
Boiling point:
365.73°C (rough estimate)
Density 
0.9415 (estimate)
refractive index 
1.7640 (estimate)
CAS DataBase Reference
641-85-0
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
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5-ALPHA-PREGNANE Usage And Synthesis

Uses

Pregnane is the steroid fundamental parent. A parent of the progesterone.

Definition

ChEBI: 5alpha-pregnane is a pregnane and a C21-steroid.

Purification Methods

Recrystallise 5-pregnane several times from Me2CO. The melting point is lowered (e.g. to 50-71o) if it is contaminated with the 5-isomer. [Butenandt et al. Chem Ber 6 4 2529 1931, Steiger & Reichstein Helv Chim Acta 21 161 1938, Beilstein 5 III 1120, 1121, 1125.]

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