Benzyl-PEG8-azide
Benzyl-PEG8-azide Basic information
- Product Name:
- Benzyl-PEG8-azide
- Synonyms:
-
- Benzyl-PEG8-azide
- Benzyl-PEG7-azide
- Benzyl-PEG7-N3
- Benzyl-PEG8-N3
- 2,5,8,11,14,17,20-Heptaoxadocosane, 22-azido-1-phenyl-
- CAS:
- 868594-42-7
- MF:
- C21H35N3O7
- MW:
- 441.53
- Mol File:
- 868594-42-7.mol
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Benzyl-PEG8-azide Usage And Synthesis
Biological Activity
Benzyl-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Benzyl-PEG8-azideSupplier
Borenpharm Co., Ltd
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Alfa Chemistry
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Nextpeptide Inc
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