Adenosine, 2-chloro-N-methyl- Chemical Properties

Boiling point:

623.5±65.0 °C(Predicted)

Density 

1.96±0.1 g/cm3(Predicted)

pka

13.06±0.70(Predicted)

Adenosine, 2-chloro-N-methyl- Usage And Synthesis

Uses

2-Chloro-N6-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

Adenosine, 2-chloro-N-methyl-(13406-50-3)Related Product Information

• Regadenoson Impurity 10
• Regadenoson Impurity 3
• Guanosine, hydrazone
• Regadenoson Impurity 57
• 9H-Purin-6-amine, 9-b-D-arabinofuranosyl-2-chloro-
• Regadenoson Impurity 5
• Methyl 2-forMyl-3,3-diMethoxypropanoate
• Xanthosine, dioxime(9CI)
• Adenosine, N-methyl-2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]-
• Regadenoson Impurity 1
• NSC 36898
• 1H-Pyrazole-4-carboxamide, 1-(6-amino-9H-purin-2-yl)-N-methyl-
• SODIUM (E)-2-(DIMETHOXYMETHYL)-3-METHOXY-3-OXOPROP-1-EN-1-OLATE
• 2-Propenoic acid, 2-(dimethoxymethyl)-3-hydroxy-, methyl ester
• CVT 3127
• sodium(Z)-2-(dimethoxymethyl)-3-methoxy-3-oxoprop-1-en-1-olate
• 9H-Purin-2-amine, 9-β-D-arabinofuranosyl-6-chloro-
• 2-[4-[(ethylamino)carbonyl]-1H-pyrazol-1-yl]adenosine