10-METHYLPHENOTHIAZINE Chemical Properties

Melting point:

99-101 °C (lit.)

Boiling point:

341.6±12.0 °C(Predicted)

Density 

1.1168 (rough estimate)

refractive index 

1.5700 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to crystal

pka

0.56±0.20(Predicted)

color 

White to Light yellow

Water Solubility 

Insoluble in water.

λmax

310nm(CHCl3)(lit.)

InChIKey

QXBUYALKJGBACG-UHFFFAOYSA-N

CAS DataBase Reference

1207-72-3(CAS DataBase Reference)

EPA Substance Registry System

10H-Phenothiazine, 10-methyl- (1207-72-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

TSCA 

Yes

HS Code 

2934.30.5000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

10-METHYLPHENOTHIAZINE Usage And Synthesis

Chemical Properties

slightly yellow to pale green crystalline powder

Uses

They are used in pharmaceutical manufacturing especially antipsychotic drugs. Also used as a stabilizer against polymerization of acrylates.

Definition

ChEBI: 10-methylphenothiazine is a member of phenothiazines.

Purification Methods

Recrystallise it (three times) from EtOH to give the -form (prisms). Recrystallisation from EtOH/*benzene gives the .-form (needles). It has also been purified by vacuum sublimation and is carefulmax 255nm (log 4.60) (pH 6.3) and 255nm in hexane. [Cymerman-Craig & Warburton Aust J Chem 9 294 1956, Beilstein 27 II 33, 27 III/IV 1215.]

10-METHYLPHENOTHIAZINE(1207-72-3)Related Product Information

• Chlorpromazine hydrochloride
• TRIFLUPROMAZINE HYDROCHLORIDE
• Ethopropazine Hydrochloride
• 10-METHYLPHENOTHIAZINE
• Promazine hydrochloride
• Phenothiazine-10-carbonyl chloride
• BENZOYL LEUCO METHYLENE BLUE
• Promethazine hydrochloride
• PERPHENAZINE
• Prochlorperazine
• methiomeprazine
• PIPERACETAZINE (250 MG)
• FLUPHENAZINE HYDROCHLORIDE
• ACEPROMAZINE MALEATE
• PROCHLORPERAZINE MALEATE
• Trifluoperazine dihydrochloride
• Phenothiazine
• Isopromethazine