Adrenomedullin (porcine)
Adrenomedullin (porcine) Basic information
- Product Name:
- Adrenomedullin (porcine)
- Synonyms:
-
- Adrenomedullin (porcine)
- Adrenomedullin (porcine) trifluoroacetate salt H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 trifluoroacetate salt (Disulfide bond)
- Adrenomedullin (porcine) trifluoroacetate salt
- CAS:
- 912862-96-5
- MF:
- C262H403N79O76S3
- MW:
- 0
- Mol File:
- Mol File
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Adrenomedullin (porcine) Chemical Properties
- form
- Solid
- Sequence
- Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: Cys16-Cys21)
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Adrenomedullin (porcine) Usage And Synthesis
Uses
Adrenomedullin (porcine) is a peptide that regulates vasodilation. Adrenomedullin (porcine) induces endothelium-dependent relaxation in rat aorta with IC50 value of 2.4 nM. Adrenomedullin (porcine) induces endothelium-independent relaxation of porcine coronary arteries with an IC50 of 27.6 nM[1].
References
[1] Yoshimoto R, et al. Effects of adrenomedullin and calcitonin gene-related peptide on contractions of the rat aorta and porcine coronary artery. Br J Pharmacol. 1998 Apr;123(8):1645-54. DOI:10.1038/sj.bjp.0701805
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