3-MORPHOLINOSYDNONIMINE
3-MORPHOLINOSYDNONIMINE Basic information
- Product Name:
- 3-MORPHOLINOSYDNONIMINE
- Synonyms:
-
- 3-MORPHOLINOSYDNONIMINE
- SIN-1
- cv664
- SIN-1 HYDROCHLORIDE (3-MORPHOLINOSYDNONI MINEHYDROCHLORIDE, LINSID
- Sin-1 16142-27-1
- 3-MorpholinosydnonmineHCl
- 3-Morpholinosydnonminehydrochloride
- 3-morpholinosydnoneimine
- CAS:
- 33876-97-0
- MF:
- C6H10N4O2
- MW:
- 170.17
- Mol File:
- 33876-97-0.mol
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3-MORPHOLINOSYDNONIMINE Chemical Properties
- storage temp.
- −20°C
- solubility
- H2O: >10 mg/mL
- form
- solid
- color
- off-white
MSDS
- Language:English Provider:SigmaAldrich
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3-MORPHOLINOSYDNONIMINE Usage And Synthesis
Uses
3-Morpholinosydnonimine is a potent vasodilator that inhibits platelet aggregation and cysteine proteases.
Definition
ChEBI: Linsidomine is a member of morpholines.
in vivo
3-Morpholinosydnonimine (0.01-0.1 mg/kg; 14 days) attenuates neointima formation in balloon-injured rat carotid arteries[4].
| Animal Model: | Six-week-old male Sprague Dawley rats (180-190 g) with a balloon-injured carotid artery model[4] |
| Dosage: | 0.01 and 0.1 mg/kg/day |
| Administration: | 14 days |
| Result: | Reduced the I/M (intima to media) ratio of the carotid artery in the group treated with 0.1 mg/kg/day. Did not change the I/M ratio of the carotid artery in the group treated with 0.01 mg/kg/day. |
IC 50
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