6-Methyl-2-pyridinemethanamine Chemical Properties

Boiling point:

55-57 °C(Press: 0.1 Torr)

Density 

1.027±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

8.75±0.39(Predicted)

Appearance

Colorless to light yellow Liquid

Safety Information

HazardClass 

IRRITANT

HS Code 

2933399990

6-Methyl-2-pyridinemethanamine Usage And Synthesis

Uses

(6-Methylpyridin-2-yl)methanamine is a pyridine derivative studied as one of the complexing agent.

Synthesis

General procedure for the synthesis of 6-methyl-2-pyridinemethanamine from 6-methyl-2-pyridinecarbonitrile: 6-methyl-2-pyridinecarbonitrile (10 g, 84.7 mmol) was dissolved in methanol (100 mL), and 10% palladium/carbon catalyst (1 g) was added under stirring conditions. The reaction mixture was stirred at room temperature overnight under the protection of nitrogen atmosphere. Upon completion of the reaction, the solid catalyst was removed by filtration and the organic solvent was removed by distillation under reduced pressure to afford 6-methyl-2-pyridinemethanamine (9 g, 87% yield).

References

[1] Patent: CN106279160, 2017, A. Location in patent: Paragraph 0213; 0218; 0219; 0220
[2] Journal of the American Chemical Society, 2015, vol. 137, # 28, p. 8888 - 8891
[3] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 12, p. 3890 - 3894

6-Methyl-2-pyridinemethanamine(6627-60-7)Related Product Information

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• Methyl propyl carbonate
• METSULFURON METHYL
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• Methanol
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• Azamethiphos
• Methyl
• 6-METHYL-2-PICOLYL-METHYLAMINE
• 4-CHLOROPYRIDINE-2,6-DICARBOHYDRAZIDE
• Pyridine-2,6-dicarbohydrazide
• Methyl bromide