Anti-CDC34 Antibody Chemical Properties

storage temp. 

-20°C

form 

buffered aqueous solution

biological source

rabbit

Safety Information

WGK Germany 

WGK 1

Storage Class

10 - Combustible liquids

Anti-CDC34 Antibody Usage And Synthesis

Biological Activity

CDC34 (cell division cycle 34) is involved in G1 to S phase transition and checkpoint function in the cell cycle. It also acts in conjugation with SCF ubiquitin ligase complexes. It initiates DNA replication by proteolytic degradation of cyclin-dependent kinases (CDKs) inhibitor. In early mitosis, it has been found with (β)-tubulin at the mitotic spindle and at the last phase of mitosis it may contribute to spindle function. It promotes cell cycle progression by directly influencing chromosome and spindle formation. CDC34, a phosphoprotein, shows kinase activity in proliferating cells by casein kinase 2 (CK2) mediated phosphorylation which further control the CDC34 cell localization and function.