PYRIMIDIN-4-YLBORONIC ACID Chemical Properties

Melting point:

>205°C (dec.)

Boiling point:

334.7±34.0 °C(Predicted)

Density 

1.33

storage temp. 

Refrigerator, under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

6.86±0.53(Predicted)

form 

Solid

color 

White to Off-White

PYRIMIDIN-4-YLBORONIC ACID Usage And Synthesis

Uses

Pyrimidin-4-ylboronic Acid is an intermediate used to prepare aldosterone synthase inhibiting pyrimidinylnaphthalenes via Suzuki cross-coupling reactions. It is also used in the synthesis of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine as a potent, orally active Src kinase inhibitor with antitumor activity.

PYRIMIDIN-4-YLBORONIC ACID(852362-24-4)Related Product Information

• PYRIMIDIN-2-YLBORONIC ACID
• PYRIMIDIN-4-YLBORONIC ACID
• 6-METHYL-2-CHLOROPYRIMIDINE-4-BORONIC ACID PINACOL ESTER
• 6-CHLORO-2-METHYLPYRIMIDINE-4-BORONIC ACID PINACOL ESTER
• 2-CHLOROPYRIMIDINE-4-BORONIC ACID PINACOL ESTER
• 2-MORPHOLINO-6-CHLOROPYRIMIDINE-4-BORONIC ACID PINACOL ESTER
• 2-(PYRROLIDIN-1-YL)-6-CHLOROPYRIMIDINE-4-BORONIC ACID PINACOL ESTER
• 2-METHYLTHIO-6-METHYLPYRIMIDINE-4-BORONIC ACID PINACOL ESTER
• 6-CHLORO-2-METHYLPYRIMIDIN-4-YL-4-BORONIC ACID
• 2-METHYLTHIO-6-CHLOROPYRIMIDINE-4-BORONIC ACID PINACOL ESTER
• 2-(1H-PYRAZOL-1-YL)-6-CHLOROPYRIMIDINE-4-BORONIC ACID PINACOL ESTER
• 2-AMINO-6-METHYLPYRIMIDIN-4-YL-4-BORONIC ACID
• 2-(METHYLTHIO)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIMIDINE
• 2-CHLOROPYRIMIDIN-4-YL-4-BORONIC ACID
• 4-CHLORO-6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIMIDINE
• 2-METHYLTHIO-6-CHLOROPYRIMIDINE-4-BORONIC ACID
• 2-AMINO-6-CHLOROPYRIMIDIN-4-YL-4-BORONIC ACID
• 6-CHLORO-2-AMINOPYRIMIDINE-4-BORONIC ACID PINACOL ESTER