Basic information Safety Supplier Related

N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE

Basic information Safety Supplier Related

N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE Basic information

Product Name:
N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE
Synonyms:
  • 4-(2-methylaminoethyl)imidazole
  • 4-(2-(methylamino)ethyl)-imidazol
  • methylhistamine
  • n(supalpha)-methylhistamine
  • n’-methylhistamine
  • n-methyl-1h-imidazole-4-ethanamin
  • IMIDAZOLE,4-(2-(METHYLAMINO)ETHYL)-
  • NA-METHYLHISTAMINE DIHYDROCHLORIDE
CAS:
673-50-7
MF:
C6H11N3
MW:
125.17
Product Categories:
  • Histamine receptor
Mol File:
673-50-7.mol
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N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE Chemical Properties

Melting point:
188-189 °C
Boiling point:
309.1±17.0 °C(Predicted)
Density 
1.050±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
pka
14.58±0.10(Predicted)
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N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE Usage And Synthesis

Uses

2-(1H-Imidazol-5-yl)-N-methylethanamine is a metabolite of histamine.

Definition

ChEBI: N-alpha-Methylhistamine is an aralkylamine.

Synthesis Reference(s)

Tetrahedron, 23, p. 239, 1967 DOI: 10.1016/S0040-4020(01)83305-6

Biological Activity

Potent histamine agonist, particularly at H 3 receptors (potency relative to histamine is 81, 185, and 270% at H 1 , H 2 and H 3 respectively). Also displays agonist properties at H 4 receptors to which it binds with moderate affinity (K i = 23 nM).

N-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDESupplier

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