(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE Basic information
- Product Name:
- (R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
- Synonyms:
-
- [R,(-)]-α-Methyl-1H-imidazole-4-ethanamine
- ( R ) -alpha-Methylhistamin x 2HBr
- R(-)-α-Methylhistamine Dihydrobromide
- (R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide
- Methylhistamine dihydrobromide (R)-(-)-alpha-
- (R)-1-(1H-iMidazol-4-yl)propan-2-aMine
- (alphaR)-alpha-Methyl-1H-imidazole-4-ethanamine
- -Methylhistamine dihydrobromide
- CAS:
- 75614-87-8
- MF:
- C6H11N3
- MW:
- 125.17
- Product Categories:
-
- Heterocyclic Building Blocks
- Histamine receptor
- Mol File:
- 75614-87-8.mol
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(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE Chemical Properties
- Density
- 1.094
- storage temp.
- Desiccate at RT
- solubility
- H2O: soluble
- form
- solid
- color
- white to off-white
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MSDS
- Language:English Provider:SigmaAldrich
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(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE Usage And Synthesis
Chemical Properties
White to off-white solid
Uses
R(-)-alpha-Methylhistamine is a potent agonist of the histamine H3-receptor.
Definition
ChEBI: An aralkylamino compound that is histamine bearing a methyl substituent at the alpha-position (the R-enantiomer).
Biological Activity
Very potent, high affinity H 3?agonist (K D = 50.3 nM) that displays > 200-fold selectivity over H 4 receptors. Inhibits H 3 -mediated histamine synthesis and release in the CNS and stimulates H 4 -mediated eosinophil shape change (EC 50 = 66 nM). Also available as part of the Histamine H 3 Receptor Tocriset™ .
(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Atop-Pharma (Shanghai) Technology Co., Ltd.
- Tel
- +86 (21) 5196-9732
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
Shanghai zhigan biotechnology co., LTD
- Tel
- zhiqianbio@126.com
CONIER CHEM AND PHARMA LIMITED
- Tel
- +8618523575427
- sales@conier.com
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(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE(75614-87-8)Related Product Information
- N'-Methyl-L-histidine methyl ester
- L-Histidine hydrochloride
- Methyl L-histidinate dihydrochloride
- L-(-)-Histidinol dihydrochloride
- H-HIS(BZL)-OME 2 HCL
- (S)-4,5,6,7-Tetrahydro-3-phenylmethyl-3H-imidazo[4,5-c]pyridine-6-carboxylic acid dihydrochloride
- H-HIS-PRO-NH2 2 HBR
- NA-BENZYL-L-HISTIDINE METHYL ESTERDIHYDR OCHLORIDE
- H-PHE-HIS-OME 2 HCL
- L-HISTIDINE, 3-(PHENYLMETHYL)-, DIHYDROCHLORIDE
- H-HIS-OET 2HCL
- H-HIS-LYS-OME 3 HCL
- (S)-2-AMINO-3-(1-METHYL-1H-IMIDAZOL-4-YL)-PROPIONIC ACID 2HCL
- H-HIS-NH2 2HCL
- (R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
- Hisphen
- (S)-(+)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
- H-HIS(TRT)-OME 2HCL